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Adrafinil is a mild central nervous stimulant used for the treatment of excessive sleepiness and fatigue, known for boosting alertness without affecting one’s normal sleep patterns. Since the drug is legal and often available without prescription it is widely used by truck drivers and night workers to stay alert, as well as students to keep awake before the exams.

Smart drug/ Nootropic Adrafinil Facts

Other names Adrafinil, Olmifon
Chemical formula C15H15NO3S
Effects Stimulating. Relieve excessive sleepiness.
Dosage One or two 300mg tablets twice a day.
Prize 40 x 300mg tablets $40
Legal status Legal.
WADA status Not approved (added to the list of prohibited substances in 2004).

Adrafinil works directly on special receptors in the brain to control alertness, without interfering with other brain functions. This way – unlike other stimulants such as amphetamines or caffeine – Adrafinil has the ability to cause mental stimulation without affecting heart rate or raising blood pressure.

Adrafinil is a prodrug, meaning that it is not active as such, but once ingested is broken down in the body into an active chemical. In the body Adrafinil is metabolized to modafinil resulting the drugs to have almost identical pharmacological effects.



The recommended Adrafinil dosage is one or two 300mg tablets twice a day. However, if the drug is used continuously one should take liver enzyme blood tests to avoid health problems.

Adrafinil is relatively safe drug. However, it should not be used along with major tranquilizers neither by people with epilepsy, liver or kidney impairment. Because the compound contains sulfur, Adrafinil generates a unique smell in the urine.

Since the drug is widely available and does not require a prescription one can easily buy it on the internet. Adrafinil was banned by the World Sports Organizations after wide abuse by sports athletes. It is believed that the drug’s ability to stimulate the brain results in better performances on the track field.

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